sciencePeptideDosage

How to Get MOTS-c: $37.50 In, 200 Units Out

How to get MOTS-c in order: no prescription exists, so vet the batch COA, apply the code for $3.75 per mg, then check the vial and the 200 units in it.

verifiedMedically reviewed byMichael Bre, MD
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MEDICAL DISCLAIMER: Educational research guidelines only. Lyophilized peptides are investigational chemical compounds and are NOT approved for human consumption, diagnosis, or therapy. Consult a licensed physician before any research application.

How to get MOTS-c is a sequence, not a search result. There is no prescription to obtain, no pharmacy to call and no clinic that can lawfully hand you a vial, so the whole process runs from a research-supply storefront to a refrigerator, and every step in between is something you can check yourself.

MOTS-c is a 16-amino-acid peptide encoded in mitochondrial DNA. Lee and colleagues characterised it in Cell Metabolism in 2015 as an AMPK-linked regulator of metabolic homeostasis, and the literature since is almost entirely cell and rodent work. The only human programme tested CB4211, an analogue rather than MOTS-c itself, through Phase 1a/1b before its sponsor wound down. No regulator has approved anything, which is precisely why step one below is the one people skip.

This page runs the sequence end to end and then does the arithmetic this site exists for: what $37.50 buys, how many milligrams that is, and what happens to the number when 2 mL of bacteriostatic water goes into the vial. If you are searching where to get MOTS-c or where can I get MOTS-c, the steps are the same; only the wording of the query changes.

Lowest cost per milligram we track

MOTS-c — Ascension Peptides

Independently assayed research material. With the code the 10 mg vial works out at $3.75/mg.

MOTS-C · 10 mg$75.00$37.50$3.75/mg10 mg / $37.50 →

Buying 3, 5 or 10 vials takes 3%, 5% or 10% off the list price. Free shipping starts at $250, which one discounted vial does not reach.

  • Two third-party assays per batch
  • Free carriage over $250
  • Same-day dispatch before 2pm CST
Discount codePEPTIDEDECK−50%

How to get MOTS-c: the sequence at a glance

Seven moves, in order. Nothing here is fast except the parts that are, and the two that people rush are the two that cost money.

  1. Establish that there is no prescription route, so the research-supply channel is the only one.
  2. Pick a supplier on published documents rather than on storefront design.
  3. Divide the price by the milligrams before anything goes in the cart.
  4. Apply the code PEPTIDEDECK and confirm the cart total moved.
  5. Check the carriage line against the $250 free-shipping threshold.
  6. Receive the parcel and match the batch code on the vial to the certificate.
  7. Store the lyophilised vial, then run the reconstitution arithmetic before any water goes near it.

Steps 1, 2 and 6 decide whether you got the compound at all. Steps 3, 4 and 7 decide what it cost per milligram. Step 5 is a small number that people forget and then find in their bank statement.

Steps 1 and 2: no prescription exists, so start with the documents

Any honest answer to how to get MOTS-c starts by closing a door.

Step 1. MOTS-c holds no marketing authorisation from the FDA, the EMA or the MHRA. There is no approved product, so no clinician can prescribe it and no pharmacy can dispense it. A 503A compounding pharmacy cannot make it either: compounding from a bulk substance requires a USP or NF monograph, status as a component of an approved drug, or a place on the FDA's 503A bulks list, and MOTS-c has none of the three. The FDA sets out that framework plainly enough to check for yourself. That leaves suppliers selling lyophilised vials labelled for laboratory research and not for human consumption. Anyone offering a prescription route is describing something that does not exist, and a search for where to get MOTS-c peptide will surface plenty of pages implying one does.

Step 2. Inside the research-supply channel, the separation between a real supplier and a reshipper is documentary. Look for four things and treat everything else as decoration.

  • A batch-coded certificate. The code on the certificate must match the code printed on the vial you are sent.
  • A named outside laboratory. Ascension Peptides publishes two per batch for its MOTS-c material, Kovera Labs on batch 24-05260628 and MZ Biolabs on batch 24-01260229. Those are the vendor's published certificates; their value is that you can check them.
  • Two methods. HPLC answers how pure, mass spectrometry answers what it is. One without the other is half a document.
  • A stated dispatch cut-off. Ascension states same-day dispatch before 2pm CST from US stock. A storefront with no cut-off anywhere is often buying your vial after you pay.

Step 3: divide before anything goes in the cart

This is the step that makes the rest comparable. A vial price describes a transaction; a per-milligram price describes the material. The division takes one line, and MOTS-c makes it easier than most peptides because there is a single SKU, so no second vial size competes for the answer.

LineFigureWhere it comes from
Vial strength10 mg, which is 10,000 mcgProduct listing and the printed label
List price$75.00Listing, reduced from a previous $89.99
Price with the code$37.50Cart total after PEPTIDEDECK is applied
Cost per mg$3.75$37.50 divided by 10
Cost per mg at list$7.50$75.00 divided by 10
CarriageCharged below $250Seven vials at $37.50 is $262.50, which clears it

Quantity is the only other lever, and it moves the number the wrong way relative to the code. Three vials are $72.75 each, five are $71.25 and ten are $67.50, all calculated on the list price, which is $7.28, $7.13 and $6.75 per mg respectively. None of those beats $3.75. The tiers are not documented as combining with the code, so treat them as alternatives rather than assuming a stack.

Step 4 and step 5: applying the code, and the carriage line

Applying it. PEPTIDEDECK goes in the discount field at checkout, before payment. The confirmation you want is numeric, not visual: the subtotal for one vial should fall from $75.00 to $37.50. If the field accepts the code but the total does not move, the code has not applied, whatever the interface says. Clear the cart and try once more before assuming anything is wrong with the order.

The carriage line. Free shipping starts at $250. A single discounted vial is $37.50, so it is a long way short, and a shipping charge on a $37.50 order is a meaningful percentage of what you paid. Two honest options exist: accept the carriage and add it to your per-milligram figure, or buy enough to clear the threshold and recalculate. Seven discounted vials come to $262.50, which clears $250 and works out at $3.75 per mg with no postage on top.

What you should not do is treat the free-shipping threshold as a reason to buy quantity you have no use for. Lyophilised peptide has a finite shelf life, and a vial bought for the postage saving is not a saving. The sibling MOTS-c coupon page covers the code mechanics in more detail, and MOTS-c price keeps the full cost breakdown.

Step 6: what to check the moment the box arrives

Everything in how to get MOTS-c up to this point was paperwork. This is the first stage where you are looking at the actual material. Five minutes here protects the whole purchase. Do it before anything goes in a fridge and before you throw the packaging away.

  • Batch code. Read the code on the vial label and match it to the certificate the vendor publishes. Character for character, not roughly.
  • Vial integrity. Check the seal, the crimp and the stopper. A vial that has lost its vacuum or shifted its cake in transit is a warranty conversation, not a research reagent.
  • The cake itself. Lyophilised peptide should be a dry cake or powder. A vial arriving as liquid, or with visible moisture, has either been pre-mixed by someone or has been through a temperature excursion.
  • Labelling. The label should state the compound, the milligram content and research-use wording. A missing milligram figure removes the denominator from every calculation you were planning to run.
  • Paperwork. Keep the invoice. It is the only record of what you paid, which is the numerator in your cost per mg, and the only basis for a refund claim.

Photograph the label and the invoice while you are doing it. A photograph taken on the day the parcel arrived is a better record than a memory of what the vial said, and it costs nothing.

If any of those fail, raise it before the return window closes rather than after. The three failures that suppliers actually deal with are wrong item, breakage in transit and non-delivery, and all three are easier to resolve in the first week.

Step 7: storage, then the reconstitution arithmetic

Lyophilised MOTS-c is stable in the dry state under refrigeration and degrades faster once it is in solution, so the vial stays dry until the arithmetic is settled. Our peptide storage guide covers the general handling case.

The interesting part is that fill volume, not price, decides what a draw costs. A 10 mg vial is 10,000 mcg however you dilute it; changing the water changes the concentration and the number of units on the barrel, not the amount of compound you own.

Bacteriostatic waterConcentrationVolume in units (U-100)10 units drawsCost of that draw at $37.50
1 mL10 mg/mL100 units1 mg (1,000 mcg)$3.75
2 mL5 mg/mL200 units500 mcg$1.88
4 mL2.5 mg/mL400 units250 mcg$0.94
5 mL2 mg/mL500 units200 mcg$0.75

Read the last column carefully, because it is a division and not a discount. At a 2 mL fill the vial holds 20 draws of 500 mcg, and $37.50 across 20 is $1.88 each. At 5 mL it holds 50 draws of 200 mcg at $0.75 each. The compound cost is $3.75 per mg in every row; only the size of the unit changed. That is worth saying out loud because a lot of peptide pricing chatter treats a bigger dilution as a bigger vial, and the underlying literature is measured in micrograms per kilogram in animals, not in syringe units. Our reconstitution guide, the syringe measurement guide and the calculator handle the general case, and the MOTS-c reference page holds the concentration tables. All of this is laboratory handling arithmetic and none of it is a protocol for a person.

Frequently Asked Questions

Can you get MOTS-c with a prescription?expand_more

No. MOTS-c is not an approved medicine in the United States, the European Union or the United Kingdom, so there is no product for a prescriber to write for. Compounding pharmacies are also closed to it, because the substance has no USP or NF monograph, is not a component of an approved drug and is not on the FDA's 503A bulks list.

Where can I get MOTS-c if pharmacies cannot supply it?expand_more

From research-chemical suppliers that sell lyophilised vials labelled for laboratory use only. The useful filter inside that channel is documentary: a batch code on the vial that matches a certificate from a named outside laboratory, both HPLC and mass spectrometry on that certificate, a stated dispatch cut-off, and a published milligram content you can divide the price by.

How do I know the discount code actually worked?expand_more

By the number, not the message. One vial should fall from $75.00 to $37.50 in the cart total once PEPTIDEDECK is applied. If the code is accepted but the subtotal is unchanged, it has not applied. Check the total again on the order confirmation, since that is the figure your cost per milligram is based on.

How long does one 10 mg vial last?expand_more

That is a division, not a fact about the vial. A 10 mg vial holds 10,000 mcg, so it contains 20 draws of 500 mcg or 50 draws of 200 mcg regardless of how much water you add. Fill volume changes the concentration and the units on the syringe barrel, not the amount of compound in the vial.

Should I buy enough vials to get free shipping?expand_more

Only if you have a use for them. The threshold is $250 and one discounted vial is $37.50, so seven vials at $262.50 clears it. Buying quantity purely to avoid a carriage charge means paying for material that has a finite shelf life once it is on the shelf, which is rarely the cheaper outcome per milligram used.

References & Citations

  1. [1]

    Lee C, Zeng J, Drew BG, et al. (2015) Cell Metab 21(3):443-454. The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance.View source →

  2. [2]

    ClinicalTrials.gov NCT03998514. A Phase 1a/1b study of CB4211, a MOTS-c analogue (CohBar, Inc.), completed.View source →

  3. [3]

    US Food and Drug Administration. Compounding and the FDA: questions and answers.View source →

  4. [4]

    Medicines and Healthcare products Regulatory Agency (MHRA). Authorisation of medicines in the United Kingdom.View source →