Sermorelin Price: $3.60 a Milligram, $3.18 on the Assay

Three prices exist for one vial, and each divides two ways depending on whether you use the label or the assay as the denominator.

The working: $99.99 minus $72.00 is $27.99, which over $99.99 is 28.0 %. $99.99 minus $36.00 is $63.99, which is 64.0 %. The code itself is exactly half of the site price, since $36.00 is $72.00 ÷ 2, and the extra 14 points come from the gap between list and site price that exists before any code is applied.

Which denominator to publish is a real editorial question and the answer is both, labelled. The label figure is comparable to any other listing, because every listing has a label. The assay figure is only comparable to another listing that publishes one, and very few do. Quoting $3.18 without saying it rests on one lot's certificate is the kind of shortcut that makes a price page useless.

Quantity tiers take 3 %, 5 % or 10 % off the list price, and they are calculated separately from the code rather than on top of it. Run the ladder and the ranking is not close.

The best published tier lands at $9.00 per labelled milligram against $3.60 with the code. A 10 % discount cannot catch a 50 % one, and buying vials in quantity to reach it makes the gap wider in absolute dollars rather than narrower.

What the ladder cannot tell you is whether a checkout applies a tier and the code together. That is a cart rule rather than a published one, so treat any stacking as something to observe on the order summary rather than something to plan an order around. The coupon page works through what discounting on this scale usually says about the list price it is taken from.

Free shipping starts at $250, and applying the code moves that line further away rather than closer, because the code halves the number the threshold is measured against.

The $12.00 is an illustration rather than a published figure, and it is there to show the shape of the effect rather than the size of it. A fixed charge divides by mass, so it lands hardest on the smallest order: on one vial it adds $1.20 per labelled milligram, which is a third of the vial price again, and on seven it adds nothing because the cart has cleared the threshold.

Whether the threshold reads the subtotal before or after the code is a checkout rule. If it reads the pre-code subtotal, three vials at the $99.99 list total $299.97 and clear it, and four at the $72.00 site price total $288.00 and clear it. If it reads the post-code subtotal, seven vials at $36.00 total $252.00 and clear it. Only the payment screen settles which.

This site's readers usually want the next division after cost per milligram, which is milligrams per millilitre. Here it produces something genuinely useful about the label gap rather than about any protocol.

The last column is constant, which is the point. The understatement does not depend on the volume chosen, because both columns divide the same two masses by the same number. Anyone calculating a concentration from the label on this lot was working with a figure 13.1 % below what the assay found, at every volume.

That is a statement about what a vial holds, not a recommendation about what to do with it. This page publishes no protocol: the only approved dosing that ever existed for this compound was paediatric and given under specialist supervision, and nothing in the modern market inherits it. For the general unit conversions our reconstitution calculator and syringe measurement guide handle any volume you enter.

The comparison readers actually want is a vial against a clinic or pharmacy programme, and this page will not fake it. Here is why it cannot be run.

A research vial publishes a price and a mass, so it divides. A compounding pharmacy fill is priced per prescription and a telehealth programme is priced per month, and neither publishes an itemised mass. Dividing a bundled monthly fee by a quantity nobody stated produces a per-milligram figure with no denominator behind it, and pages that publish one are usually trying to make the vial look good.

What can be said honestly is what each side includes. The vial includes a certificate you can read before paying and nothing else. The programme includes an evaluation, a prescriber, laboratory work and a preparation made against a prescription. Those are different products, and the fact that one is cheaper per gram of powder is not an argument for anything.

The route exists at all because of the compound's history. It was marketed as Geref by EMD Serono under NDA 019863 and NDA 020443, the therapeutic approval dated 1997-09-26, and both are now discontinued with the FDA record recording that the product was not discontinued or withdrawn for safety or effectiveness reasons. Section 503A permits compounding from a bulk substance that was a component of an approved drug product, so a pharmacy route survives the discontinuation. Our channel comparison sets the four routes side by side.

A rate per milligram measures one thing well and is silent on three others worth naming.

• Testing scope. The certificate for lot 38-01260229 reports purity of 99.79 % by HPLC-UV-MS across 4 detected peaks and a quantity of 11.31 mg. It carries no endotoxin test and no sterility test. That scope belongs to the lot, not to the product or the seller, and it is the single most useful thing to check in a minute.
• Evidence for the marketed use. PubMed returns 332 records mentioning the compound, 3 with it in the title and 29 tagged as clinical trials. Searched alongside anti-aging the count is zero, and ClinicalTrials.gov registers no studies naming it. The approvals that existed covered paediatric growth hormone deficiency and pituitary diagnostics.
• Anyone in the loop. A vial arrives with a document and no clinician. That is a structural feature of the channel rather than a criticism of the seller.

Price is the easiest thing to compare and the least informative thing to compare alone. The order that works is certificate, then identity, then testing scope, then arithmetic, because only the last step has a number in it and the first three decide whether that number describes anything real.